

| Dosage | Package | Price per Dose | Price | |
|---|---|---|---|---|
| 400mg | 180 pills | $1.65 | $350.22 $297.69 Best Price Popular | |
| 400mg | 120 pills | $1.77 | $249.28 $211.89 | |
| 400mg | 90 pills | $1.90 | $200.34 $170.29 | |
| 400mg | 60 pills | $2.04 | $143.75 $122.19 | |
| 400mg | 30 pills | $2.28 | $81.04 $68.89 |
Mesalazine, also called mesalamine, is an anti-inflammatory medicine used to treat inflammation of the colon. It belongs to the class of 5-aminosalicylic acids (5-ASA). The medicine can be taken as tablets, capsules, or rectal formulations like suppositories or enemas, depending on the part of the bowel affected. It is designed to act mainly in the lining of the colon, with limited absorption into the rest of the body. Doctors prescribe mesalazine for conditions where the colon is inflamed but the disease is not too advanced. The exact formulation chosen aims to deliver the active drug to the site of inflammation while reducing systemic exposure. The dose and formulation you receive should align with your doctor’s guidance and your disease location.
Mesalazine is commonly used to treat mild to moderate ulcerative colitis and to prevent flare ups in people who have had episodes of colitis. It is also used in some cases of Crohn's disease when the colon is involved. For maintenance therapy, paying attention to dosing helps keep symptoms at bay over time. It is not a cure, but it reduces symptoms such as urgency, abdominal pain, and blood in the stool. Your doctor may start with a higher dose and then step down to a lower, ongoing dose. In certain patients, combination therapy with other anti-inflammatory medicines may be recommended. The choice of formulation—oral, rectal, or a combination—helps tailor treatment to the areas most affected by your disease.
Mesalazine works mainly in the colon itself. It reduces inflammation by blocking inflammatory mediators in the gut lining and by acting as a local antioxidant. Some formulations release the drug further along the intestine to target different segments. Because most of the drug stays in the gut, systemic side effects are less common than with some other anti-inflammatory medicines. The exact mechanism is complex and still studied, but the result is calmer mucosa and fewer signs of an active flare. The local action helps limit inflammation while aiming to preserve overall intestinal function.
Common side effects include mild nausea, stomach upset, heartburn, headache, or diarrhea. Some people may notice a rash or flushing. If you develop severe stomach pain, yellowing of skin, dark urine, swelling, fever, or confusion, seek medical help promptly. Less often, mesalazine can affect kidney function or liver enzymes, so doctors may monitor blood tests during treatment. Tell your clinician about kidney disease, liver disease, or a history of allergic reactions before starting therapy. People with significant kidney impairment may need dose adjustments or alternative medicines. Mesalazine can interact with other medicines such as NSAIDs or other anti-inflammatory drugs, so always tell your healthcare provider about all drugs you take. Do not take this medicine if you are allergic to salicylates or if you have had a severe reaction to mesalazine in the past. For safety, store at room temperature away from moisture. Pregnant or breastfeeding people should use this medicine only if clearly needed and advised by a clinician. For buyers who value privacy, the pharmacy offers no-ID checkout and anonymous purchases with Bitcoin and other cryptocurrencies, along with discreet worldwide shipping. Orders can be placed using cryptocurrency and shipped to many destinations without revealing sensitive personal details. Privacy-focused options help keep medical purchases discreet while you follow medical guidance. Always follow the prescribed dosing and do not share your medicines with others.
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